Digital microfluidics and hydrogels
Hydrogels are networks of hydrophilic polymer chains that are swollen with water, and they are useful for a wide range of applications because they provide stable niches for immobilizing proteins and cells. Hydrogels have very recently been combined with digital microfluidics: and systematically addressed by droplets of reagents. The combination of hydrogels and digital microfluidics is an exciting new area for a wide range of applications; papers describing our efforts in this area are listed below.
Luk, V.N.; Fiddes, L.K.; Luk, V.M.; Kumacheva, E.; Wheeler, A.R. "Digital Microfluidic-Hydrogel Microreactors for Proteomics" Proteomics 2012, 12, 1310-1318.Fiddes, L.K.; Luk, V.N.; Au, S.H.; Ng, A.H.C.; Luk, V.M.; Kumacheva, E.; Wheeler, A.R. "Hydrogel Discs for Digital Microfluidics" Biomicrofluidics 2012, 6, 014112.