Optoelectronic Tweezers

"Optoelectronic Tweezers" (OET) is a manipulation tool that is related to digital microfluidics (DMF). In both techniques, electric potentials are applied to a series of electrodes to allow for the manipulation of fluids and particles. A key difference is – in conventional DMF, the electrodes are permanent, while in OET, the electrodes are ‘virtual’ – that is, ‘virtual electrodes’ are defined by the projection of light onto an unpatterned photoconductive material. In effect, this allows for the generation of electrodes with arbitrary size and position, that can be moved in time by projecting a series of moving light patterns onto the device. Papers describing our work with OET are listed below, and a short movie illustrating our OET-driven microrobot can be viewed here.

Zhang, S.; Scott, E.Y.; Singh, J.; Chen, Y.; Zhang, Y.; Elsayed, M.; Chamberlain, M.D.; Shakiba, N.; Adams, K.; Yu, S.; Morshead, C.M.; Zandstra, P.W.; Wheeler, A.R. "The optoelectronic microrobot: A versatile toolbox for micromanipulation" Proceedings of the National Academy of Science, U.S.A. 2019, 116 (30), 14823-14828. Supporting Info.

Zhang, S.; Shakiba, N.; Chen, Y.; Zhang, Y.; Tian, P.; Singh, J.; Chamberlain, M.D.; Satkauskas, M.; Flood, A.G.; Kherani, N.P.; Yu, S.; Zandstra, P.W.; Wheeler, A.R. "Patterned Optoelectronic Tweezers: A New Scheme for Selecting, Moving, and Storing Dielectric Particles and Cells" Small, 2018, 45, 1803342. Supplementary: Info, Movie 1, Movie 2, Movie 3, Movie 4, Movie 5, Movie 6.

Zhang, S.; Nikitina, A.; Chen, Y.; Zhang, Y.; Liu, L.; Flood, A.G.; Juvert, J.; Chamberlain, M.D.; Kherani, N.P.; Neale, S.L.; Wheeler, A.R. "Escape from an optoelectronic tweezer trap: experimental results and simulations" Optics Express, 2018, 26, 5300-5309. Supplementary: Movie 1, Movie 2; Movie 3; Movie 4.